Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang et al. · Nature · 2009 · 2.1K citations · Full text

Glutamine Metabolism, Mitochondrial Function, Mitochondrial Dynamic +8

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

David R. Wise, Ralph J. DeBerardinis, Anthony Mancuso et al. · Proceedings of the National Academy of Sciences · 2008 · 1.9K citations · Full text

Mitochondrial Glutaminolysis, Molecular Biology, Metabolic Remodeling +23

Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStress

Maiko Ogata, Shin‐ichiro Hino, Atsushi Saito et al. · Molecular and Cellular Biology · 2006 · 1.8K citations · Full text

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

Paul Nicklin, Philip J. Bergman, Bailin Zhang et al. · Cell · 2009 · 1.7K citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +8