Pediatric Dermatology · 2004 · 25 citations · 15 references
MedicinePediatricsPharmacologyPediatric Clinical PharmacologyPediatric DermatologyPediatric ImmunologyDrug-induced Skin ReactionsNecrosisPediatric Adverse Drug ReactionsPediatric ToxicologyEpidermal Toxicity
Toxic epidermal necrolysis (TEN) is a severe, life-threatening disorder that usually affects adults. It is often drug induced. We report an instance of a severe case of TEN in a 6-year-old boy, probably induced by acetaminophen, and less likely by codeine. A lymphocyte stimulation test could not identify the culprit drug. Treatment with intravenous immunoglobulin seemed to halt the disease progression.
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Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome
I. García‐Doval, Laurence Le Cleach, Hélène Bocquet et al. · Archives of Dermatology · 2000 · 493 citations