The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat

Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain

Alfred Mansour, Henry Khachaturian, M. E. Suzanne Lewis et al. · Pain · 1988 · 980 citations

Precise Localization, Pain Medicine, Pharmacotherapy +23

Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for delta opioid binding sites.

V. Erspamer, Pietro Melchiorri, Giuliana Falconieri–Erspamer et al. · Proceedings of the National Academy of Sciences · 1989 · 457 citations · Full text

Delta Receptors, Molecular Pharmacology, Biochemistry +13

Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice.

Essam E. Abdelhamid, Marjia Sultana, Philip S. Portoghese et al. · Journal of Pharmacology and Experimental Therapeutics · 1991 · 426 citations

Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.

Peter W. Schiller, Tin Nguyen, Grazyna Weltrowska et al. · Proceedings of the National Academy of Sciences · 1992 · 239 citations · Full text

Unprecedented Delta Selectivity, Pharmacotherapy, Opioid Peptide Analogs +18

Repeated cocaine administration upregulates K and μ, but not δ, opioid receptors

Ellen M. Unterwald, Joshua M. Rubenfeld, Mary Jeanne Kreek · Neuroreport · 1994 · 232 citations