Mary Jeanne Kreek

Single-nucleotide polymorphism in the human mu opioid receptor gene alters β-endorphin binding and activity: Possible implications for opiate addiction

Cherie E. Bond, K. Steven LaForge, Mingting Tian et al. · Proceedings of the National Academy of Sciences · 1998 · 1.1K citations

Medicine, Molecular Genetics, Pharmacology +17

Stress-Induced Cocaine Craving and Hypothalamic-Pituitary-Adrenal Responses Are Predictive of Cocaine Relapse Outcomes

Rajita Sinha, Miguel García, Prashni Paliwal et al. · Archives of General Psychiatry · 2006 · 539 citations

Nursing, Psychiatry, Psychology +17

Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis

Stephanie S. O’Malley, Suchitra Krishnan‐Sarin, Conor K. Farren et al. · Psychopharmacology · 2002 · 497 citations

Medicine, Pharmacology, Psychology +16

1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial

Johan Kakko, Kerstin Svanborg, Mary Jeanne Kreek et al. · The Lancet · 2003 · 474 citations

Medicine, Pharmacotherapy, Addiction Psychiatry +14

Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states

Rajita Sinha, Makram Talih, Robert T. Malison et al. · Psychopharmacology · 2003 · 370 citations

Medicine, Endocrinology, Neuroscience +16