Human BAC library: construction and rapid screening

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

H. Shizuya, Bruce W. Birren, U J Kim et al. · Proceedings of the National Academy of Sciences · 1992 · 1.7K citations · Full text

Life Sciences, Biotechnology, Genetics +17

Cloning of Large Segments of Exogenous DNA into Yeast by Means of Artificial Chromosome Vectors

David Burke, Georges F. Carle, Maynard V. Olson · Science · 1987 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +17

A new bacteriophage P1–derived vector for the propagation of large human DNA fragments

P.A. loannou, Chris T. Amemiya, Jeffrey Garnes et al. · Nature Genetics · 1994 · 850 citations

Life Sciences, Microbiology, Molecular Biology +14

A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones

J. Riley, Rachel Butler, Donald Ogilvie et al. · Nucleic Acids Research · 1990 · 646 citations · Full text

Life Sciences, Biotechnology, Genetics +12

Construction and Characterization of a Human Bacterial Artificial Chromosome Library

Ung‐Jin Kim, Bruce W. Birren, Tatiana I. Slepak et al. · Genomics · 1996 · 454 citations

Life Sciences, Genetics, Molecular Biology +12