International Journal for Numerical Methods in Engineering · 2006 · 66 citations · 42 references
EngineeringBioengineeringBiomedical EngineeringBiomaterialsNanomaterialsNanotechnologyBiofluid MechanicsElectrokinetic PhenomenaMacromolecular Assembly ModelingDeformable ModelsElectrical PropertiesElectrokinetic FlowMaxwell Stress TensorSelective DepositionStress TensorStress-energy TensorViscous Effects
Abstract A new method is proposed for modelling the electrokinetic‐induced mechanical motion of particles in a fluid domain under an applied electric field. In this method, independent solid meshes move in a fixed background field mesh that models the fluid and the electric field. This simple strategy removes the need for expensive mesh updates. Furthermore, the reproducing kernel particle functions enable efficient coupling of various immersed deformable solids with the surrounding viscous fluid in the presence of an applied electric field. The electric force on a particle is calculated by the Maxwell stress tensor method. For the first time, three‐dimensional assembly of nano/biomaterials of various geometries and electrical properties have been comprehensively studied using the new method. Simulation of the dynamic process of electro‐manipulation of individual and multiple cells agrees well with experimental data. Preliminary results for selective deposition of viruses and stretching of a DNA molecule are also presented. Copyright © 2006 John Wiley & Sons, Ltd.
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