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Synthesis of 2′-O-guanidinopropyl-modified nucleoside phosphoramidites and their incorporation into siRNAs targeting hepatitis B virus

2′-O-guanidinopropyl-modified Nucleoside PhosphoramiditesBiochemistryNatural SciencesDrug DiscoveryAntiviral Drug DevelopmentOligonucleotideMolecular BiologyAntiviral DrugHepatitis B VirusAntiviral CompoundBiomolecular Engineering