ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

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Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel et al. · Neurology · 1993 · 3.8K citations · Full text

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Learning enhances adult neurogenesis in the hippocampal formation

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The prevalence of dementia and Alzheimer's disease in Shanghai, China: Impact of age, gender, and education

Mingyuan Zhang, Robert Katzman, David P. Salmon et al. · Annals of Neurology · 1990 · 1.1K citations

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Differential Effects of Apolipoproteins E3 and E4 on Neuronal Growth in Vitro

Britto P. Nathan, Stefano Bellosta, David A. Sanan et al. · Science · 1994 · 802 citations

Life Sciences, Neurobiology, Neuroscience +17