Concepedia

COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates

Vincent Fagan, Sarah Bonham, Michael P. Carty, Patricia Saenz‐Méndez, Leif A. Eriksson, Fawaz Aldabbagh

Bioorganic & Medicinal Chemistry · 2012 · 35 citations · 17 references

DOI

Concepts

References

17

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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How well does a restrained electrostatic potential (RESP) model perform in calculating conformational energies of organic and biological molecules?

Junmei Wang, Piotr Cieplak, Peter A. Kollman · Journal of Computational Chemistry · 2000 · 4K citations

, , +17

NAD(P)H:Quinone Oxidoreductase 1: Role as a Superoxide Scavenger

David Siegel, Daniel L. Gustafson, Donna L. Dehn et al. · Molecular Pharmacology · 2004 · 448 citations

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The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction.

R Li, Mario A. Bianchet, Paul Talalay et al. · Proceedings of the National Academy of Sciences · 1995 · 336 citations · Full text

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Reductase Enzyme Expression Across the National Cancer Institute Tumor Cell Line Panel: Correlation With Sensitivity to Mitomycin C and EO9

Sara A. Fitzsimmons, Paul Workman, Michael R. Grever et al. · JNCI Journal of the National Cancer Institute · 1996 · 235 citations · Full text

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