Concepedia

Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41

Shibo Jiang, Srinivasa R. Tala, Hong Lü, Peng Zou, İlker Avan, Tarek S. Ibrahim, Nader E. Abo‐Dya, Abdelmotaal Abdelmajeid, Asim K. Debnath, Alan R. Katritzky

Bioorganic & Medicinal Chemistry Letters · 2011 · 34 citations · 5 references

DOI

Concepts

References

5

Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

David C. Chan, Christine T. Chutkowski, Peter S. Kim · Proceedings of the National Academy of Sciences · 1998 · 475 citations

, , +13

The entry of entry inhibitors: A fusion of science and medicine

John P. Moore, Robert W. Doms · Proceedings of the National Academy of Sciences · 2003 · 277 citations · Full text

, , +17

N-Substituted Pyrrole Derivatives as Novel Human Immunodeficiency Virus Type 1 Entry Inhibitors That Interfere with the gp41 Six-Helix Bundle Formation and Block Virus Fusion

Shibo Jiang, Hong Lü, Shuwen Liu et al. · Antimicrobial Agents and Chemotherapy · 2004 · 264 citations

, , +17

Design, Synthesis, and Structure−Activity Relationship of a Novel Series of 2-Aryl 5-(4-Oxo-3-phenethyl-2-thioxothiazolidinylidenemethyl)furans as HIV-1 Entry Inhibitors

Alan R. Katritzky, Srinivasa R. Tala, Hong Lü et al. · Journal of Medicinal Chemistry · 2009 · 99 citations

, , +17

Design, Synthesis, and Biological Activity of Novel 5-((Arylfuran/1<i>H</i>-pyrrol-2-yl)methylene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-ones as HIV-1 Fusion Inhibitors Targeting gp41

Shibo Jiang, Srinivasa R. Tala, Hong Lü et al. · Journal of Medicinal Chemistry · 2010 · 82 citations

, , +17