Hoxb13 mutations cause overgrowth of caudal spinal cordand tail vertebrae

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Knockout Mouse, Embryonic Stem Cell, Lineage Plasticity +12

A<i>cre</i>-transgenic mouse strain for the ubiquitous deletion of<i>loxP</i>-flanked gene segments including deletion in germ cells

Frieder Schwenk, Udo Baron, Klaus Rajewsky · Nucleic Acids Research · 1995 · 1.3K citations

Knockout Mouse, Germ Cell Fate, Transgenic Mouse Models +15

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

Osamu Chisaka, Mario R. Capecchi · Nature · 1991 · 851 citations

Knockout Mouse, Developmental Biology, Developmental Genetics +6

Wnt-3a regulates somite and tailbud formation in the mouse embryo.

Shinji Takada, Kevin L. Stark, Martin J. Shea et al. · Genes & Development · 1994 · 794 citations · Full text

Organ Development, Mesoderm Formation, Embryology +18

Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11

Allan Peter Davis, David P. Witte, Hsiu Mei Hsieh‐Li et al. · Nature · 1995 · 602 citations

Knockout Mouse, Hoxa-11 Andhoxd-11, Molecular Neuroscience +4