Metabolism Studies in C liac Disease

Abstract

Since the publication of Cheadle's paper' in 1903, the presence of excess of fat in the foeces has attracted much notice as the most characteristic signi of the metabolic disturbainee in cceliac disease. It ha,s beein recognized that associated with this disturbance of fat absorption, there occuirs also a defective retention of minerals and an excessive loss of nitroge.n in the feeces. In consequence some attention hias been paid to the effect of varying the composition of the dietarv, especially fromi the therapeuitic standpoint. The inter- relationship of the disturbanices in the absorption of the various elements of the diet is a m4atter of importance both from the practical point of view, an(d l)ecause of the possible value in the explanation of other metabolic disor(lers.