Concepedia

Regioselective Synthesis of 1,3,5-Triaryl-4-alkylpyrazoles:  Novel Ligands for the Estrogen Receptor

Ying Huang, John A. Katzenellenbogen

Organic Letters · 2000 · 194 citations · 4 references

DOI

Concepts

Abstract

[reaction: see structure] A regioselective synthesis of 4-alkyl-1,3,5-triarylpyrazoles has been developed for the preparation of unsymmetrically substituted systems of interest as ligands for the estrogen receptor.

References

4

Solid-state spectroelectrochemistry of crosslinked donor bound polymer films

Frank B. Kaufman, Edward M. Engler · Journal of the American Chemical Society · 1979 · 171 citations

, , +11

Key Intermediates in Combinatorial Chemistry:  Access to Various Heterocycles from α,β-Unsaturated Ketones on the Solid Phase

Andreas L. Marzinzik, Eduard Felder · The Journal of Organic Chemistry · 1998 · 100 citations

, , +17

N.m.r. Spectra and Stereoisomerism in Pyrazolines

M.J. Michelson · The Journal of Organic Chemistry · 1962 · 47 citations

, , +6

Hydroxylated 2,3-diarylindenes: Synthesis, estrogen receptor binding affinity, and binding orientation considerations

Gregory M. Anstead, Chad S. Peterson, John A. Katzenellenbogen · Journal of Steroid Biochemistry · 1989 · 20 citations

, , +14