Physicochemical characterization of anionic lipid-based ternary siRNA complexes

An Inverted Hexagonal Phase of Cationic Liposome-DNA Complexes Related to DNA Release and Delivery

Ilya Koltover, Tim Salditt, Joachim O. Rädler et al. · Science · 1998 · 1.3K citations · Full text

Natural Sciences, Biochemistry, Biophysics +17

On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids

IM Hafez, Norbert Maurer, P.R. Cullis · Gene Therapy · 2001 · 595 citations

Life Sciences, Biochemistry, Molecular Biology +10

The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation

Ranit Kedmi, Noa Ben-Arie, Dan Peer · Biomaterials · 2010 · 539 citations

Life Sciences, Immunology, Toxicology +17

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

Marian DiFiglia, Miguel Sena‐Esteves, Kathryn Chase et al. · Proceedings of the National Academy of Sciences · 2007 · 411 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cells

Olivier Zelphati, L S Uyechi, Lee G Barron et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1998 · 309 citations

Life Sciences, Biochemistry, Molecular Biology +14