Concepedia

Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model

Tetsuhiro Tanaka, Ichiro Kojima, Takamoto Ohse, Julie R. Ingelfinger, Stephen Adler, Toshiro Fujita, Masaomi Nangaku

Laboratory Investigation · 2005 · 239 citations · 49 references

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49

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

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HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text

, , +16

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein, Jonathan Gleadle, Luke A. McNeill et al. · Cell · 2001 · 3.3K citations · Full text

, , +9

Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

David Lando, Daniel J. Peet, Dean A. Whelan et al. · Science · 2002 · 1.5K citations

, , +14

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.

Hui-Qiao Tian, Steven L. McKnight, David W. Russell · Genes & Development · 1997 · 1.3K citations · Full text

, , +16