Concepedia

A Serine Protease, HtrA2, Is Released from the Mitochondria and Interacts with XIAP, Inducing Cell Death

Yasuyuki Suzuki, Yuzuru Imai, Hiroshi Nakayama, Kazuko Takahashi, Koji Takio, Ryōsuke Takahashi

Molecular Cell · 2001 · 1.1K citations · 27 references

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27

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

Chunying Du, Min Fang, Yucheng Li et al. · Cell · 2000 · 3.5K citations · Full text

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Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

Anne M. Verhagen, Paul G. Ekert, Miha Pakusch et al. · Cell · 2000 · 2.3K citations · Full text

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X-linked IAP is a direct inhibitor of cell-death proteases

Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen et al. · Nature · 1997 · 1.9K citations · Full text

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IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases

Quinn L. Deveraux · The EMBO Journal · 1998 · 1.4K citations · Full text

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The c‐IAP‐1 and c‐IAP‐2 proteins are direct inhibitors of specific caspases

Natalie Roy · The EMBO Journal · 1997 · 1.3K citations · Full text

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