Effects of resveratrol-related hydroxystilbenes on the nitric oxide production in macrophage cells: structural requirements and mechanism of action

Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

Meishiang Jang, Lining Cai, George Udeani et al. · Science · 1997 · 4.9K citations

Medicine, Oncology, Pharmacology +17

Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor

Barry D. Gehm, Joanne M. McAndrews, Pei-Yu Chien et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations

Life Sciences, Biochemistry, Endocrinology +13

Resveratrol Suppresses TNF-Induced Activation of Nuclear Transcription Factors NF-κB, Activator Protein-1, and Apoptosis: Potential Role of Reactive Oxygen Intermediates and Lipid Peroxidation

Sunil K. Manna, Asok Mukhopadhyay, Bharat B. Aggarwal · The Journal of Immunology · 2000 · 874 citations

Life Sciences, Botany, Plant Sciences +15

Resveratrol Inhibits Cyclooxygenase-2 Transcription and Activity in Phorbol Ester-treated Human Mammary Epithelial Cells

Kotha Subbaramaiah, Wen Jing Chung, Pedro Michaluart et al. · Journal of Biological Chemistry · 1998 · 792 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Suppression of nitric oxide synthase and the down‐regulation of the activation of NFκB in macrophages by resveratrol

Shu‐Huei Tsai, Shoei‐Yn Lin‐Shiau, Jen‐Kun Lin · British Journal of Pharmacology · 1999 · 508 citations · Full text

Life Sciences, Immunology, Immunoregulation +12