Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

Hiroshi Takayanagi, Sunhwa Kim, Takako Koga et al. · Developmental Cell · 2002 · 2.6K citations · Full text

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Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

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Histone Modifications, Molecular Biology, Epigenetics +20

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

Hailing Hsu, David L. Lacey, Colin R. Dunstan et al. · Proceedings of the National Academy of Sciences · 1999 · 1.6K citations · Full text

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c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

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Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

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Sirt1 Function, Genetics, Apoptosis +19