Studies on the glomerular microcirculatory actions of manidipine and its modulation of the systemic and renal effects of endothelin

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations · Full text

Life Sciences, Cell Biology, Physiology +9

THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN 1

Homer W. Smith, N.P. Finkelstein, Lucy Aliminosa et al. · Journal of Clinical Investigation · 1945 · 1.6K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +9

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

Gilberto De Nucci, Ranjeny Thomas, Pedro D’Orléans-Juste et al. · Proceedings of the National Academy of Sciences · 1988 · 1.4K citations · Full text

Medicine, Pharmacology, Physiology +12

Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors.

Kiyohiko Takahashi, Tarek Nammour, Masao Fukunaga et al. · Journal of Clinical Investigation · 1992 · 513 citations · Full text

Pharmacy, Pharmacology, Renal Pathophysiology +12

Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways.

K F Badr, John Murray, Matthew D. Breyer et al. · Journal of Clinical Investigation · 1989 · 417 citations · Full text

Medicine, Cell Biology, Physiology +16