An approach towards the synthesis of oligomers containing a N-2-hydroxyethyl-aminomethylphosphonate backbone: A novel PNA analogue

Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

Peter E. Nielsen, Rolf H. Berg, Ole Buchardt · Science · 1991 · 3.3K citations

Life Sciences, Biomolecular Engineering, Molecular Biology +17

Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone

Ole Buchardt, Peter E. Nielsen, Rolf H. Berg · Journal of the American Chemical Society · 1992 · 736 citations

Life Sciences, Biochemistry, Molecular Biology +12

Recognition of guanine and adenine in DNA by cytosine and thymine containing peptide nucleic acids (PNA)

Peter E. Nielsen, Ole Buchardt, Rolf H. Berg · Journal of the American Chemical Society · 1992 · 266 citations

Pharmacy, Biochemistry, Molecular Biology +10

N-Phosphonomethyl Dipeptides and Their Phosphonate Prodrugs, a New Generation of Neutral Endopeptidase (NEP, EC 3.4.24.11) Inhibitors

Stéphane De Lombaert, Mark D. Erion, Jenny Tan et al. · Journal of Medicinal Chemistry · 1994 · 80 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Solid phase synthesis of directly linked PNA-DNA-hybrids

Frank Bergmann, Willi Bannwarth, Steve Tam · Tetrahedron Letters · 1995 · 69 citations

Pharmacy, Biotechnology, Materials Science +10