Minocycline Alleviates Sevoflurane-Induced Cognitive Impairment in Aged Rats

Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study

Pjm Pierre Cluitmans, LS Rasmussen, P.J. Houx et al. · The Lancet · 1998 · 2.4K citations · Full text

Neuropsychology, Aging, Geriatrics +6

Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

Vesna Jevtović‐Todorović, Richard E. Hartman, Yukitoshi Izumi et al. · Journal of Neuroscience · 2003 · 2K citations · Full text

Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

Du Chu Wu, Vernice Jackson‐Lewis, Miquel Vila et al. · Journal of Neuroscience · 2002 · 1.2K citations · Full text

Neurodegenerative Diseases, Nigrostriatal Dopaminergic Neurons, Nigrostriatal Dopaminergic Pathway +15

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

Minghua Chen, Victor Ona, Mingwei Li et al. · Nature Medicine · 2000 · 1K citations

Delays Mortality, Cell Death, Degenerative Disease +8

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

Juha Yrjänheikki, Tiina Tikka, Riitta Keinänen et al. · Proceedings of the National Academy of Sciences · 1999 · 1K citations · Full text

Cerebrovascular Disease, Pharmacotherapy, Focal Cerebral Ischemia +23