Fluorescent analogues of quinoline reveal amine ligand loss from cis and trans platinum(II) complexes in cancer cells

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed · 1987 · 3.8K citations

Medicine, Pharmacology, Chemotherapy +11

Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation

Anne Marie J. Fichtinger-Schepman, J. L. VAN DER VEER, Jeroen H. J. Den Hartog et al. · Biochemistry · 1985 · 1K citations

Medicine, Oncology, Pharmacology +8

Activation of the trans geometry in platinum antitumor complexes. Synthesis, characterization, and biological activity of complexes with the planar ligands pyridine, N-methylimidazole, thiazole, and quinoline. Crystal and molecular structure of trans-dichlorobis(thiazole)platinum(II)

Marijo Van Beusichem, Nicholas P. Farrell · Inorganic Chemistry · 1992 · 233 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance

Lloyd R. Kèlland, Swee Y. Sharp, Ciaran F. O’Neill et al. · Journal of Inorganic Biochemistry · 1999 · 207 citations

Medicine, Medicinal Chemistry, Oncology +11

Cytostatic trans-platinum(II) complexes

Nicholas P. Farrell, Tam Ha, Jean Pierre Souchard et al. · Journal of Medicinal Chemistry · 1989 · 178 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8