Inhibition of hepatic cholesterol synthesis and S-3-hydroxy-3-methylglutaryl-CoA reductase by mono and bicyclic monoterpenes administered in vivo

Micro assay for 3-hdyroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts

David J. Shapiro, Jeffrey L. Nordstrom, Jonathan J. Mitschelen et al. · Biochimica et Biophysica Acta (BBA) - Enzymology · 1974 · 407 citations

L-cell Fibroblasts, Hepatology, Biochemistry +14

Active and inactive forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the liver of the rat. Comparison with the rate of cholesterol synthesis in different physiological states.

Michael S. Brown, J L Goldstein, John Dietschy · Journal of Biological Chemistry · 1979 · 308 citations · Full text

Different Physiological States, Oxysterol, 3-Hydroxy-3-methylglutaryl Coenzyme +10

Effect of alterations of the specific activity of the intracellular acetyl CoA pool on apparent rates of hepatic cholesterogenesis

John M. Dietschy, Michael S. Brown · Journal of Lipid Research · 1974 · 162 citations · Full text

Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme a reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation

Thomas S. Ingebritsen, Hyo-Sa Lee, Rex A. Parker et al. · Biochemical and Biophysical Research Communications · 1978 · 142 citations

Aldo-keto Reductase, Inactivating Enzyme, Biochemistry +8

Factors affecting the diurnal variation in the level of β-hydroxy-β-methylglutaryl coenzyme A reductase and cholesterol-synthesizing activity in rat liver

Richard E. Dugan, Linda L. Slakey, Anita V. Briedis et al. · Archives of Biochemistry and Biophysics · 1972 · 111 citations

Cholesterol-synthesizing Activity, Energy Metabolism, Biochemistry +9