Bruce Middleton

Human liver long-chain 3-hydroxyacyl-coenzyme a dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria

K. Carpenter, R. J. Pollitt, Bruce Middleton · Biochemical and Biophysical Research Communications · 1992 · 147 citations

Life Sciences, Biochemistry, Molecular Biology +11

Inhibition of hepatic cholesterol synthesis and S-3-hydroxy-3-methylglutaryl-CoA reductase by mono and bicyclic monoterpenes administered in vivo

Richard J. Clegg, Bruce Middleton, G. D. Bell et al. · Biochemical Pharmacology · 1980 · 85 citations

Life Sciences, Biochemistry, Pharmacology +14

Mitochondrial Fatty Acid β-Oxidation in the Human Eye and Brain: Implications for the Retinopathy of Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency

Tiina Tyni, Anders Paetau, Arnold W. Strauss et al. · Pediatric Research · 2004 · 81 citations

Life Sciences, Biochemistry, Ophthalmology +16

The synthesis and characterisation of 2-methylacetoacetyl coenzyme A and its use in the identification of the site of the defect in 2-methylacetoacetic and 2-methyl-3-hydroxybutyric aciduria

Bruce Middleton, K. Bartlett · Clinica Chimica Acta · 1983 · 81 citations

Life Sciences, Biochemistry, Chemistry +8

The mechanism of inhibition of β-oxidation by aspirin metabolites in skin fibroblasts from Reye’s syndrome patients and controls

J. F. T. Glasgow, Bruce Middleton, Raymond C. Moore et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 1999 · 59 citations

Medicine, Biochemistry, Pharmacology +11