Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells - Concepedia

Concepedia

Publication | Open Access

Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells

DOI Full Paper Access

37

Citations

34

References

2012

Year

Igor Tsaur, Jasmina Makarević, Eva Juengel, Martin Gasser, A-M Waaga-Gasser, M. Kurosch, M. Reiter, Saskia Wedel, Georg Bartsch, Axel Haferkamp,

British Journal of Cancer

Abstract

Chronic RAD001 treatment caused resistance development characterised by distinct modification of the integrin-expression profile, driving prostate cancer cells towards high motility.

References

	Year	Citations

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