Recombinant Respiratory Syncytial Viruses with Deletions in the NS1, NS2, SH, and M2-2 Genes Are Attenuated in Vitro and in Vivo

Orthomyxoviridae: The Viruses and Their Replication.

Robert A. Lamb, Griffith D. Parks · 1996 · 2.8K citations

Life Sciences, Biology, Microbiology +10

Generation of Bovine Respiratory Syncytial Virus (BRSV) from cDNA: BRSV NS2 Is Not Essential for Virus Replication in Tissue Culture, and the Human RSV Leader Region Acts as a Functional BRSV Genome Promoter

Ursula J. Buchholz, Stefan Finke, Karl‐Klaus Conzelmann · Journal of Virology · 1999 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

Adolfo García‐Sastre, Andrej Egorov, Demetrius Matassov et al. · Virology · 1998 · 1K citations

Life Sciences, Infectious Diseases, Molecular Biology +17

Defectiveness of Interferon Production and of Rubella Virus Interference in a Line of African Green Monkey Kidney Cells (Vero)

Jan Desmyter, Joseph L. Melnick, William E. Rawls · Journal of Virology · 1968 · 517 citations · Full text

Life Sciences, Cell Biology, Microbiology +14

Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development.

Peter L. Collins, M G Hill, Ena Camargo et al. · Proceedings of the National Academy of Sciences · 1995 · 447 citations

Life Sciences, Infectious Diseases, Molecular Biology +17