Glycosylation at 158N of the Hemagglutinin Protein and Receptor Binding Specificity Synergistically Affect the Antigenicity and Immunogenicity of a Live Attenuated H5N1 A/Vietnam/1203/2004 Vaccine Virus in Ferrets

Weijia Wang, Bin Lü, Helen Zhou, +5

Journal of Virology

VaccinationVeterinary VaccineAllergyVaccine DevelopmentAmino Acids +12

Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (flumist) derived from cold-adapted a/ann arbor/6/60

Hong Jin, Bin Lü, Helen Zhou, +5

Virology

VaccinationTemperature SensitivityVaccine DevelopmentVaccine TargetVirology +7

One prophage WO gene rescues cytoplasmic incompatibility in <i>Drosophila melanogaster</i>

J. Dylan Shropshire, Jungmin On, Emily M. Layton, +2

Proceedings of the National Academy of Sciences

Recombinant Respiratory Syncytial Viruses with Deletions in the NS1, NS2, SH, and M2-2 Genes Are Attenuated in Vitro and in Vivo

Hong Jin, Helen Zhou, Xing Cheng, +3

Virology

Viral ReplicationMolecular VirologyRespiratory DiseasesPathogenesisViral Pathogenesis +5

Generation of Live Attenuated Novel Influenza Virus A/California/7/09 (H1N1) Vaccines with High Yield in Embryonated Chicken Eggs

Weijia Wang, Helen Zhou, Amorsolo L. Suguitan, +5

Journal of Virology

GeneticsImmunologyFlu VaccinationViral Structural ProteinInfluenza Vaccines +16

Improvement of Influenza A/Fujian/411/02 (H3N2) Virus Growth in Embryonated Chicken Eggs by Balancing the Hemagglutinin and Neuraminidase Activities, Using Reverse Genetics

Bin Lü, Helen Zhou, Dan Ye, +2

Journal of Virology

Two residues in the hemagglutinin of A/Fujian/411/02-like influenza viruses are responsible for antigenic drift from A/Panama/2007/99

Hong Jin, Helen Zhou, Hui Liu, +5

Virology

Virus StructureViral EvolutionA/fujian/411/02-like Influenza VirusesMolecular BiologyVirology +4

Recombinant Human Respiratory Syncytial Virus (RSV) from cDNA and Construction of Subgroup A and B Chimeric RSV

Hong Jin, David K. Clarke, Helen Zhou, +4

Virology

Viral ReplicationSubgroup AImmunologyVirologyMedicine +2

Imparting Temperature Sensitivity and Attenuation in Ferrets to A/Puerto Rico/8/34 Influenza Virus by Transferring the Genetic Signature for Temperature Sensitivity from Cold-Adapted A/Ann Arbor/6/60

Hong Jin, Helen Zhou, Bin Lü, +1

Journal of Virology

ImmunologyStrain SelectionDonor VirusFlu VaccinationVirus Transmission +18

Respiratory Syncytial Virus That Lacks Open Reading Frame 2 of the M2 Gene (M2-2) Has Altered Growth Characteristics and Is Attenuated in Rodents

Hong Jin, Xing Cheng, Helen Zhou, +2

Journal of Virology