Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

Kazuya Shimoda, Jan van Deursent, Mark Y. Sangster et al. · Nature · 1996 · 1.3K citations

Life Sciences, Genetics, Immunology +16

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase

Noah Craft, Yuriy Shostak, Michael Carey et al. · Nature Medicine · 1999 · 984 citations

Medicine, Cancer Biology, Oncology +15

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

Naftaly Meydan, T Grunberger, Harjit Dadi et al. · Nature · 1996 · 912 citations

Medicine, Hematology, Pharmacology +9

Role of IRS-2 in insulin and cytokine signalling

Xiao Jian Sun, Ling-Mei Wang, Yitao Zhang et al. · Nature · 1995 · 850 citations

Life Sciences, Endocrinology, Molecular Biology +12