Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature · 1997 · 5.5K citations

Host Response, Toll-like Receptors, Signal Transduction +10

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Bruno Lemaître, Émmanuelle Nicolas, Lydia Michaut et al. · Cell · 1996 · 3.9K citations · Full text

Biology, Potent Antifungal Response, Natural Sciences +10

HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

Nalp3 Inflammasome, Aluminum Salts, Membrane Biology +5

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

Manfred B. Lutz, Nicole A. Kukutsch, Alexandra Ogilvie et al. · Journal of Immunological Methods · 1999 · 3K citations

Regenerative Medicine, Cell Therapy, Advanced Culture Method +13