Evidence for an association between immune responsiveness of chicken to (T, G)‐A–L and the major histocompatibility system

Abstract

Abstract The antibody response of different inbred chicken lines to the synthetic polypeptide (T, G)‐A–L is described. It is shown by analysis of backcross hybrids that a major gene controlling this response is linked to the major histocompatibility system of chicken. This result is discussed with respect to its relation to the structure of major histocompatibility systems of mammals.