Gallic acid downregulates matrix metalloproteinase‐2 (MMP‐2) and MMP‐9 in human leukemia cells with expressed Bcr/Abl

Abstract

Our data indicate that MMP-2 and MMP-9 downregulation in gallic acid treated K562 cells are mediated through suppression of JNK1-mediated c-Jun/ATF-2 and Akt/ERK-mediated c-Jun/c-Fos pathways, respectively.