Concepedia

A highly sensitive canine telemetry model for detection of QT interval prolongation: Studies with moxifloxacin, haloperidol and MK-499

Alyssa Chaves, Gloria J. Zingaro, Michael Yordy, Katherine Bustard, Saoirse E. O’Sullivan, Alema Galijatovic-Idrizbegovic, H. Schuck, D.B. Christian, C.M. Hoe, Richard J. Briscoe

Journal of Pharmacological and Toxicological Methods · 2007 · 35 citations · 31 references

DOI

Concepts

References

31

Cellular Basis for the Normal T Wave and the Electrocardiographic Manifestations of the Long-QT Syndrome

Gan‐Xin Yan, Charles Antzelevitch · Circulation · 1998 · 990 citations

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Testing the Statistical Certainty of a Response to Increasing Doses of a Drug

John W. Tukey, Joseph L. Ciminera, Joseph F. Heyse · Biometrics · 1985 · 489 citations

, , +10

A Randomized Evaluation of the Effects of Six Antipsychotic Agents on QTc, In the Absence and Presence of Metabolic Inhibition

Edmund P. Harrigan, Jeffrey Miceli, Richard Anziano et al. · Journal of Clinical Psychopharmacology · 2004 · 358 citations

, , +14

Clinical Evaluation of QT/QTc Prolongation and Proarrhythmic Potential for Nonantiarrhythmic Drugs: The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use E14 Guideline

Börje Darpö, T Nebout, Philip T. Sager · The Journal of Clinical Pharmacology · 2006 · 321 citations

, , +13

Interactions of a Series of Fluoroquinolone Antibacterial Drugs with the Human Cardiac K<sup>+</sup>Channel HERG

Jiesheng Kang, Lin Wang, Xiaoliang Chen et al. · Molecular Pharmacology · 2001 · 280 citations

, , +17