Role of the Cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) Domain in Trafficking and Stabilization of Kv11.1 Channels

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy et al. · Cell · 1995 · 2.3K citations · Full text

Long Qt Syndrome, Cardiomyopathy, Genetics +9

Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus

João H. Morais‐Cabral, Alice A. Lee, Steven L. Cohen et al. · Cell · 1998 · 438 citations · Full text

Crystal Structure, Engineering, Biochemistry +7

Most LQT2 Mutations Reduce Kv11.1 (hERG) Current by a Class 2 (Trafficking-Deficient) Mechanism

Corey L. Anderson, Brian P. Delisle, Blake D. Anson et al. · Circulation · 2006 · 409 citations

Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel.

Roland Schönherr, Stefan H. Heinemann · The Journal of Physiology · 1996 · 326 citations · Full text

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

Stephen J. Huffaker, Jingshan Chen, Kristin K. Nicodemus et al. · Nature Medicine · 2009 · 255 citations · Full text

Neurobiological Mechanism, Neuropsychology, Brain Isoform +14