Photocontrol of Triple-Helix Formation by Using Azobenzene-Bearing Oligo(thymidine)

Abstract

Upon irradiation, reversible modulation of triple-helix formation occurs. A model double helix is formed from oligo(T) and oligo(dA). In the presence of a second oligo(T) modified with an azobenzene moiety, the binding strength of the triple helix is dependent upon the configuration of the azobenzene, a feature controlled by light (see picture). The length of the oligomers and position of the azobenzene affect the helix-binding strength. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2000/z14180_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.