Concepedia

Oligonucleotide Stability

Oligonucleotide Stability is a biochemical property that denotes the resistance of an oligonucleotide to degradation or denaturation under physiological or experimental conditions, distinguished by its dependence on nucleotide sequence, chemical modifications, and secondary structure formation.

422

Publications

23.5K

Citations

1.6K

Authors

458

Institutions

Publications per year

2017–2026

32

Parents

Publications

422

A Fluorescence-Based Method for Determining the Surface Coverage and Hybridization Efficiency of Thiol-Capped Oligonucleotides Bound to Gold Thin Films and Nanoparticles

Linette M. Demers, Chad A. Mirkin, Robert C. Mucic et al. · Analytical Chemistry · 2000 · 1.1K citations

, , +17

Improved Nearest-Neighbor Parameters for Predicting DNA Duplex Stability

John SantaLucia, Hatim T. Allawi, P. Ananda Seneviratne · Biochemistry · 1996 · 846 citations

, , +16

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice.

Sudhir Agrawal, Jamal Temsamani, Jin Tang · Proceedings of the National Academy of Sciences · 1991 · 560 citations · Full text

, , +11

The stability of helical polynucleotides: Base contributions

Howard DeVoe, Ignacio Tinoco · Journal of Molecular Biology · 1962 · 491 citations

, , +14

Stability and Properties of Double and Triple Helices: Dramatic Effects of RNA or DNA Backbone Composition

Richard W. Roberts, Donald M. Crothers · Science · 1992 · 476 citations

, , +17

1–5 of 422

Authors

1.6K

  1. SA
    Sudhir Agrawal

    Idera Pharmaceuticals (United States), United States

    11 publications · 1.2K citations

    11

    h-index

  2. FS
    Frank Seela

    Osnabrück University, Germany

    8 publications · 230 citations

    8

    h-index

  3. RL
    Robert L. Letsinger

    Northwestern University, United States

    7 publications · 1.4K citations

    7

    h-index

  4. TB
    Tom Brown

    University of Southampton, United Kingdom

    6 publications · 229 citations

    6

    h-index

  5. BR
    Bernard Rayner

    Centre National de la Recherche Scientifique, France

    5 publications · 362 citations

    5

    h-index

1–5 of 1.6K

Institutions

458

  1. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    85 publications

    3.6K citations

  2. Ionis Pharmaceuticals (United States)

    Carlsbad, United States

    15 h-index

    69 publications

    5.2K citations

  3. Inserm

    Paris, France

    15 h-index

    48 publications

    2.2K citations

  4. The University of Tokyo

    Tokyo, Japan

    8 h-index

    44 publications

    3.3K citations

  5. Institut Gustave Roussy

    Villejuif, France

    7 h-index

    20 publications

    459 citations

  6. University of Southampton

    Southampton, United Kingdom

    7 h-index

    22 publications

    614 citations

  7. Osnabrück University

    Osnabrück, Germany

    7 h-index

    25 publications

    653 citations

  8. University of Alabama at Birmingham

    Birmingham, United States

    6 h-index

    28 publications

    2.1K citations

1–8 of 458

Venues

  1. Nucleic Acids Research

    67 publications · 4.1K citations

    36

    h-index

  2. Journal of the American Chemical Society

    JACS · 26 publications · 1.9K citations

    25

    h-index

  3. Biochemistry

    29 publications · 2.3K citations

    21

    h-index

  4. Bioconjugate Chemistry

    13 publications · 425 citations

    12

    h-index

  5. PubMed

    Repository · 12 publications · 961 citations

    12

    h-index

1–5