The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism

Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation.

Charles F. Sing, Jean Davignon · PubMed · 1985 · 708 citations

Life Sciences, Genetics, Molecular Genetics +16

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

Vassilis I. Zannis, Jan L. Breslow · Biochemistry · 1981 · 562 citations

Life Sciences, Biochemistry, Genetics +10

Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations.

Christian Ehnholm, Matti Lukka, T Kuusi et al. · Journal of Lipid Research · 1987 · 407 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Abnormal in vivo metabolism of apolipoprotein E4 in humans.

Richard E. Gregg, Loren A. Zech, Ernst J. Schaefer et al. · Journal of Clinical Investigation · 1986 · 348 citations · Full text

Life Sciences, Biochemistry, Lipid Biochemistry +16

Deletion in the Gene for the Low-Density-Lipoprotein Receptor in a Majority of French Canadians with Familial Hypercholesterolemia

Helen H. Hobbs, Michael S. Brown, David W. Russell et al. · New England Journal of Medicine · 1987 · 301 citations

Medicine, Genetics, Molecular Genetics +17