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Multiple Genetic Factors in Olanzapine-Induced Weight Gain in Schizophrenia Patients

DOI

89

Citations

0

References

2008

Year

Hiroshi Ujike, Akira Nomura, Yukitaka Morita, Akiko Morio, Yuko Okahisa, Tatsuya Kotaka, Masafumi Kodama, Takeshi Ishihara, Shigetoshi Kuroda
The Journal of Clinical Psychiatry

Abstract

We identified genetic variants of 5-HT(2A) and 5-HT(2C) receptors, the G-protein beta-3 subunit, and the adrenergic receptor beta-3, as genetic risk factors for olanzapine-induced weight gain, and they showed additive genetic effects on weight gain.