Archives of Ophthalmology · 1986 · 212 citations · 24 references
Surgical OncologyOphthalmologySelective RemovalOculoplasticsSoft Tissue SurgeryMinimally Invasive ProcedureSurgeryWound HealingOcular PathologyTotal Microscopic ControlMedicineOcular TissuePlastic SurgeryMicrographic Surgery
Because it allows for the total microscopic control of excision, micrographic surgery is a solution to the problem of determining the exact extent of cancers of the eyelids. The control of excision is achieved by removing successive layers of the affected tissues and microscopically examining the entire undersurface of each layer by the systematic use of frozen sections. The reliability of the method is attested by the five-year cure rates of 99% in 1,773 cases of basal cell carcinoma and of 98.1% in 213 cases of squamous cell carcinoma of the eyelids. Also important is the minimal removal of uninvaded tissue that is feasible because of the precise localization and selective removal of the clinically unpredictable cancerous outgrowths. This saving of normal tissue permits some innovative techniques of wound management.
24
Frederic E. Mohs · Archives of surgery · 1941 · 423 citations
SQUAMOUS-CELL EPITHELIOMA OF THE SKIN A STUDY OF 256 CASES
Albert C. Broders · Annals of Surgery · 1921 · 352 citations · Full text
MODES OF SPREAD OF CANCER OF SKIN
Frederic E. Mohs · Archives of Dermatology · 1952 · 180 citations