Inhibitory effect of the antimalarial agent artesunate on collagen-induced arthritis in rats through nuclear factor kappa B and mitogen-activated protein kinase signaling pathway

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

J. Frederick Woessner · The FASEB Journal · 1991 · 3.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

Zuoning Han, David L. Boyle, Lufen Chang et al. · Journal of Clinical Investigation · 2001 · 775 citations · Full text

Life Sciences, Immunology, Molecular Biology +13

NF-κB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

Alexei Miagkov, Chadwick E. Brown, John Didsbury et al. · Proceedings of the National Academy of Sciences · 1998 · 465 citations · Full text

Life Sciences, Immunology, Pathobiology +15

Role of interleukin‐4 and interleukin‐10 in murine collagen‐induced arthritis. Protective effect of interleukin‐4 and interleukin‐10 treatment on cartilage destruction

Leo A. B. Joosten, Erik Lubberts, Patrick Durez et al. · Arthritis & Rheumatism · 1997 · 399 citations

Veterinary Medicine, Immunology, Pathobiology +17

Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis

Georg Schett, M Tohidast-Akrad, Josef S. Smolen et al. · Arthritis & Rheumatism · 2000 · 375 citations

Medicine, Immunology, Pathobiology +17