Josef S. Smolen

Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial

Ravinder N. Maini, E. William St. Clair, Ferdinand C. Breedveld et al. · The Lancet · 1999 · 2.4K citations

Medicine, Pharmacology, Pharmacotherapy +17

Autoantigen microarrays for multiplex characterization of autoantibody responses

William H. Robinson, Carla DiGennaro, Wolfgang Hueber et al. · Nature Medicine · 2002 · 677 citations

Life Sciences, Immunology, Molecular Biology +16

Osteoclasts are essential for TNF-α–mediated joint destruction

Kurt Redlich, Silvia Hayer, Roméo Ricci et al. · Journal of Clinical Investigation · 2002 · 534 citations · Full text

Medicine, Immunology, Pathobiology +17

Osteoprotegerin Is a Risk Factor for Progressive Atherosclerosis and Cardiovascular Disease

Stefan Kiechl, Georg Schett, Gregor K. Wenning et al. · Circulation · 2004 · 507 citations · Full text

Medicine, Cardiology, Bone Metabolism +14

Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis

Georg Schett, M Tohidast-Akrad, Josef S. Smolen et al. · Arthritis & Rheumatism · 2000 · 375 citations

Medicine, Immunology, Pathobiology +17