Evidence-based Complementary and Alternative Medicine · 2011 · 217 citations · 122 references
Life SciencesBiochemistryMicrobiologyMarine BiotechnologyMarine MicrobiologyMarine PhysiologyMarine Bioactive CompoundsMarine Microbial MetabolismMarine Microbial PhysiologyMarine Natural Product BiosynthesisMarine Natural ProductsPigment ProductionBioactive Compounds From Marine BacteriaBioactive PigmentsMarine Bacterial MetabolitesMarine Microbial Natural ProductsMarine PigmentsMicrobial MetabolitesMicrobial PigmentsPigments
Marine natural product research has surged, with marine bacterial pigments gaining interest for their diverse pharmacological activities. This review surveys pigmented compounds from marine bacteria, evaluating their biological, pharmacological, and commercial applications, as well as their biosynthesis and physiological roles. The paper details the chemical structures of these pigments and outlines their biosynthetic pathways and physiological functions.
Research into natural products from the marine environment, including microorganisms, has rapidly increased over the past two decades. Despite the enormous difficulty in isolating and harvesting marine bacteria, microbial metabolites are increasingly attractive to science because of their broad-ranging pharmacological activities, especially those with unique color pigments. This current review paper gives an overview of the pigmented natural compounds isolated from bacteria of marine origin, based on accumulated data in the literature. We review the biological activities of marine compounds, including recent advances in the study of pharmacological effects and other commercial applications, in addition to the biosynthesis and physiological roles of associated pigments. Chemical structures of the bioactive compounds discussed are also presented.
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