Analysis of the Liposidomycin Gene Cluster Leads to the Identification of New Caprazamycin Derivatives

Abstract

En route: The liposidomycin biosynthetic gene cluster has been identified, cloned and heterologously expressed. A comparison with the gene cluster of the structurally related caprazamycins supports the proposed pathway to liponucleoside formation and led to the identification of new sulfated caprazamycin derivatives. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.