Homozygosity of MSH2 c.1906G→C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

Hans F. A. Vasen, Jukka‐Pekka Mecklin, P. Meera Khan et al. · Diseases of the Colon & Rectum · 1991 · 2.2K citations

Medicine, Genetics, Oncology +17

Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis

JT Wijnen, FH Menko, JH Kleibeuker et al. · Gastroenterology · 1996 · 824 citations · Full text

Life Sciences, Genetics, Oncology +16

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

Niels de Wind, Marleen Dekker, Anton Berns et al. · Cell · 1995 · 792 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer

Païvi Peltomäki · Gastroenterology · 1997 · 754 citations · Full text

Life Sciences, Genetics, Oncology +17

Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes.

Stephen N. Thibodeau, Amy J. French, Patrick C. Roche et al. · PubMed · 1996 · 466 citations

Life Sciences, Genetics, Oncology +17