Concepedia

Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis

Christiana Davis, Brian J. Hawkins, Subbiah Ramasamy, Krishna M. Irrinki, Bruce A. Cameron, Khalid Islam, Varsha P. Daswani, Patrick J. Doonan, Yefim Manevich, Muniswamy Madesh

Free Radical Biology and Medicine · 2009 · 113 citations · 49 references

DOI

Concepts

References

49

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce et al. · Nature Chemical Biology · 2005 · 3K citations

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

, , +15

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He, Lai Wang, Lin Miao et al. · Cell · 2009 · 2.2K citations

, , +10

Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide

Rafael Radí, Joseph S. Beckman, Kenneth M. Bush et al. · Archives of Biochemistry and Biophysics · 1991 · 2.2K citations

, , +16

Identification of RIP1 kinase as a specific cellular target of necrostatins

Alexei Degterev, Junichi Hitomi, Megan Germscheid et al. · Nature Chemical Biology · 2008 · 2K citations · Full text

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