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Increased DNA Methyltransferase 1 (DNMT1) Protein Expression Correlates Significantly with Poorer Tumor Differentiation and Frequent DNA Hypermethylation of Multiple CpG Islands in Gastric Cancers

Tsuyoshi Etoh, Yae Kanai, Saori Ushijima, Tohru Nakagawa, Yukihiro Nakanishi, Mitsuru Sasako, Seigo Kitano, Setsuo Hirohashi

American Journal Of Pathology · 2004 · 291 citations · 39 references

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39

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

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CpG island methylator phenotype in colorectal cancer

Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota et al. · Proceedings of the National Academy of Sciences · 1999 · 2.5K citations

, , +17

Incidence and functional consequences of <i>hMLH1</i> promoter hypermethylation in colorectal carcinoma

James G. Herman, Asad Umar, Kornélia Polyák et al. · Proceedings of the National Academy of Sciences · 1998 · 1.9K citations · Full text

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

Ina Rhee, Kurtis E. Bachman, Ben Ho Park et al. · Nature · 2002 · 1.2K citations

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COBRA: a sensitive and quantitative DNA methylation assay

Zhongguo Xiong, Peter W. Laird · Nucleic Acids Research · 1997 · 1.2K citations · Full text

, , +15