A Comparison of the Relaxant Effects of Olprinone and Aminophylline on Methacholine-Induced Bronchoconstriction in Dogs

Abstract

We compared the relaxant effects of olprinone and aminophylline on methacholine-induced bronchoconstriction in dogs. The relaxant effects of olprinone are independent of plasma epinephrine, whereas the aminophylline effects may be partly caused by an increase in plasma epinephrine.