T J Torphy

Pharmacologic profile of SK&F 104353: a novel, potent and selective peptidoleukotriene receptor antagonist in guinea pig and human airways.

Douglas W.P. Hay, Roseanna M. Muccitelli, Stephanie S. Tucker et al. · PubMed · 1987 · 147 citations

Lung Inflammation, Pharmacotherapy, Experimental Pharmacology +18

Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody.

David C. Underwood, Ruth R. Osborn, S J Newsholme et al. · American Journal of Respiratory and Critical Care Medicine · 1996 · 141 citations

Inflammation, Asthma, Inflammatory Lung Disease +14

Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.

David C. Underwood, Ruth R. Osborn, Linda Novak et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 127 citations

Lower esophageal sphincter relaxation is associated with increased cyclic nucleotide content

T J Torphy, Cordelia Fine, Marta Maria Burman et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1986 · 95 citations

Molecular Physiology, Esophagus, Biochemistry +13

Functional antagonism in canine tracheal smooth muscle: inhibition by methacholine of the mechanical and biochemical responses to isoproterenol.

T J Torphy, G. A. Rinard, Martha G. Rietow et al. · Journal of Pharmacology and Experimental Therapeutics · 1983 · 77 citations