Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Umut Özcan, Qiong Cao, Erkan Yılmaz et al. · Science · 2004 · 3.8K citations

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Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose.

Richard N. Bergman, Lawrence S. Phillips, Claudio Cobelli · Journal of Clinical Investigation · 1981 · 1.6K citations · Full text

Medicine, Endocrinology, Physiology +16

Quantification of the Relationship Between Insulin Sensitivity and β-Cell Function in Human Subjects: Evidence for a Hyperbolic Function

Steven E. Kahn, Ronald L. Prigeon, David K. McCulloch et al. · Diabetes · 1993 · 1.4K citations

Medicine, Endocrinology, Physiology +17

Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α

Samar I. Itani, Neil B. Ruderman, Frank Schmieder et al. · Diabetes · 2002 · 1.4K citations · Full text

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Inhibition of Ceramide Synthesis Ameliorates Glucocorticoid-, Saturated-Fat-, and Obesity-Induced Insulin Resistance

William L. Holland, Joseph T. Brozinick, Liping Wang et al. · Cell Metabolism · 2007 · 1.2K citations · Full text

Life Sciences, Biochemistry, Endocrinology +14