Synthesis and Characterization of Potent and Selective Agonists of the Neuronal Cannabinoid Receptor (CB1)

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, L Hanŭs, Aviva Breuer et al. · Science · 1992 · 5.6K citations

Brain Constituent, Neurotransmitter, Cannabinoid Pharmacology +17

Molecular characterization of a peripheral receptor for cannabinoids

Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar · Nature · 1993 · 5K citations

Cannabis Use, Molecular Pharmacology, Functional Selectivity +7

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

Lisa A. Matsuda, Stephen J. Lolait, Michael Brownstein et al. · Nature · 1990 · 5K citations

Cannabis Use, Molecular Pharmacology, Biochemistry +11

Cannabinoid receptor localization in brain.

Miles Herkenham, A B Lynn, M.D. Little et al. · Proceedings of the National Academy of Sciences · 1990 · 2.3K citations · Full text

High Densities, Cannabinoid Pharmacology, Social Sciences +17