Concepedia

Isolation and Identification of Peptide Degradation Products of Heat Stressed Pramlintide Injection Drug Product

Carla Hekman, Wade Demond, Trupti Dixit, Steve F Mauch, Marc Nuechterlein, Anna Stepanenko, Jon D. Williams, Ming Ye

Pharmaceutical Research · 1998 · 27 citations · 13 references

DOI

Concepts

References

13

The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation.

Jeffrey L. Cleland, Melissa Powell, S J Shire · PubMed · 1993 · 542 citations

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Critical Reviews in Therapeutic Drug Carrier Systems

Mandip Sachdeva, Valtencir Zucolotto · 2020 · 400 citations

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Effects of amino acid sequence, buffers, and ionic strength on the rate and mechanism of deamidation of asparagine residues in small peptides.

Ruth Tyler‐Cross, Verne Schirch · Journal of Biological Chemistry · 1991 · 372 citations · Full text

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Chemical Pathways of Peptide Degradation. III. Effect of Primary Sequence on the Pathways of Deamidation of Asparaginyl Residues in Hexapeptides

Kamlesh C. Patel, Ronald T. Borchardt · Pharmaceutical Research · 1990 · 177 citations

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Sequence and structure determinants of the nonenzymatic deamidation of asparagine and glutamine residues in proteins

H.T. Wright · Protein Engineering Design and Selection · 1991 · 166 citations

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